Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma
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modern surgical techniques in treatment of patients with cleft lip & cleft palate
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15 صفحه اولSkin reaction to capsaicin in patients with Systemic Lupus Erythematosus compared to that in healthy controls
Background: The interaction between nervous and immune systems has been under investigation. Transient receptor potential vanilloid type 1(TRPV1) is a ligand gated calcium channel expressed by sensory neurons which mediates neurogenic inflammatory response. Substance p which can be released following exposure to capsaicin is a TRPV1 inducer, shown to have altered concentration and function in m...
متن کاملRaltitrexed with Uracil-Tegafur or Mitomycin C as Salvage Treatment in Advanced Colorectal Cancer
Colorectal cancer (CRC) is the third most common neoplasm in Turkey and in the world and their incidence has increased in recent years (Jemal et al., 2010; Karaca et al., 2011). At diagnosis, 30-40 per cent of colorectal cancer patients have metastatic disease. For patients with advanced colorectal cancer treatment is usually palliative and mainly consists of systemic chemotherapy (Scheithauer ...
متن کاملActivity and toxicity of oxaliplatin plus raltitrexed in 5-fluorouracil refractory metastatic colorectal adeno-carcinoma.
BACKGROUND This study evaluated the antitumor efficacy and safety of a novel oxaliplatin/raltitrexed combination in pretreated advanced colorectal cancer patients. PATIENTS AND METHODS Forty-five patients with 5-fluorouracil-refractory metastatic colorectal cancer received raltitrexed 3.0 mg/m2 as a 15-minute intravenous (i.v.) infusion, followed 45 min later by l-OHP 130 mg/m2 i.v. as 2-h ve...
متن کاملThe prognostic significance of a postoperative systemic inflammatory response in patients with colorectal cancer
BACKGROUND Recently, a preoperative systemic inflammatory response has been reported to be a prognostic factor in patients with colorectal cancer (CRC). However, the prognostic significance of a systemic inflammatory response in the early stage after surgery in patients with CRC is unknown. The aim of this retrospective study was to evaluate the prognostic significance of a postoperative system...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2002
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6600520